2024 Keratin 14 promoter

Keratin 14 promoter

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WebThe figure shows representative hematoxylin and eosin stainings, as well as p63, keratin K5, and keratin K14 immunostainings in epidermis from healthy donors, AK and cSCC … WebKeratin synthesis is regulated at the level of transcription. Each keratin genes appears to be regulated by a characteristic constellation of transcription factors and DNA binding sites. Often these occur in clusters …

Transcriptional regulation analysis and the potential …

WebDetection of K14 mRNA by RT-PCR in murine ovaries and immunohistochemical identification of the K14 protein in oocytes demonstrates that the human K14 promoter … Web21 mrt. 2024 · KRT14 (Keratin 14) is a Protein Coding gene. Diseases associated with KRT14 include Dermatopathia Pigmentosa Reticularis and Naegeli-Franceschetti … lameck ditto nchi yangu mp3 download

Sequence of the functional human keratin K14 promoter

WebKeratin 14 was the first type I keratin sequence determined. [5] Keratin 14 is also known as cytokeratin-14 ( CK-14) or keratin-14 ( KRT14 ). In humans it is encoded by the … Web20 aug. 2013 · Transgenic mice expressing the mouse interleukin 33 (IL-33) gene driven by a keratin 14 promoter were generated. The skin-selective expression of the IL-33 gene was enhanced, and intense immunofluorescence for IL-33 was evident in … Web5 mei 2009 · 14 publications Note The disease is caused by variants affecting the gene represented in this entry Description A form of epidermolysis bullosa simplex, a group of skin fragility disorders characterized by skin blistering due to cleavage within the basal layer of keratinocytes, and erosions caused by minor mechanical trauma. lameck ditto sukuma damu download

Hematopoietic Stem and Progenitor Cell Activation During Chronic ...

E2F-1 induces proliferation-specific genes and suppresses

Web13 apr. 2024 · Gene duplication is thought to be a central process in evolution to gain new functions. The factors that dictate gene retention following duplication as well paralog gene divergence in sequence, expression and function have been extensively studied. However, relatively little is known about the evolution of promoter regions of gene duplicates and … WebKRT14-Cre mice are viable, fertile, normal in size and do not display any gross abnormalities. The mice can be used as a tool model to study gene function in ectoderm … lameck ditto sukuma damu audio downloadWebKeratin 14 Krt14 Promoter Driven Cre Recombinase Mice, supplied by The Jackson Laboratory, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed … lameck ditto song moyo sukuma damu

"Web9 jul. 2009 · Keratin 14 promoter restricts gene expression to keratinocytes of the epidermal basal layer, CD11c promoter to dendritic cells and fascin promoter only to mature dendritic cells. The use of plasmids with tissue-specific promoter resulted in significant, but very low protein expression, as compared to that obtained with ubiquitous … " - Keratin 14 promoter

Keratin 14 promoter

Keratins in Skin Epidermal Development and Diseases

Web6 jun. 2000 · Promoter activity for the proliferation-associated genes, cdc2 and keratin 14, are inhibited during squamous differentiation. This inhibition can be inhibited by overexpression of E2F-1 in ... Web5 nov. 2024 · Epidermal keratinocyte (KC), the major cell type in the skin epidermis, plays critical roles in forming a permeability barrier to separate internal organs from external stimuli. Keratins, constituting about 30–80% of the total protein in KCs, form the major intermediate filament cytoskeleton of KC. Keratins consist of 54 unique genes in humans …

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WebHuman Keratin 14 Krt14 Promoter, supplied by The Jackson Laboratory, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - …

Web004782 STOCK Tg(KRT14-cre)1Amc/J A congenic version of this strain is available as Stock No. 018964 . The K14-Cre transgene has a human keratin 14 promoter directing … Please use this form to enter mouse-related technical questions, comments, … MGI Workshops. If you would like to host an MGI workshop at your institution, … Still need help finding something? Call 1.800.422.6423 (US) 1.207.288.5845 … Mouse phenome database, MPD...an integrated resource to explore … EEO Statement. The Jackson Laboratory provides equal employment … JAX Center for Addiction Biology. The JAX Center for Addiction Biology is an … As a nonprofit research institution, The Jackson Laboratory is able to pursue … Select the newsletters and research areas that interest you. We will send you … Web1 jul. 1999 · Abstract Transgenic mice that overexpress the anti-apoptotic gene bcl-xL under the control of the keratin 14 promoter have significantly shorter hair than non-transgenic …

Web9 mei 2012 · According to addition mutation of K14 promoter assay with different length of p53-binding site, both p53 and p63 could up-regulate the mutant keratin 14 promoter with whole-site of p53-binding site (Fig. 9B). Therefore, different length of p53-binding site could determinate the gene regulated by different p53 family members. WebKeratin 14 is a keratin isoform strongly expressed by highly proliferative basal cells in chemically induced papilloma. The promoter of this keratin isoform was used to drive …

Web20 aug. 2013 · Transgenic mice expressing the mouse interleukin 33 (IL-33) gene driven by a keratin 14 promoter were generated. The skin-selective expression of the IL-33 gene …

WebKeratin 14 is a member of the type I keratin family of intermediate filament proteins. Keratin 14 was the first type I keratin sequence determined. Keratin 14 is also known as cytokeratin-14 (CK-14) or keratin-14 (KRT14).In humans it is encoded by the KRT14 gene.. Keratin 14 is usually found as a heterodimer with type II keratin 5 and form the … jersey mike\u0027s carolina beach ncWeb14 feb. 1995 · The K14 keratin is an intermediate filament produced in squamous epithelia. This tissue-specific expression is directed by the promoter (pK14) of the K14 gene … lameck ditto sukuma damu mp3 downloadWebTo determine the role of vitamin D receptor in the regulation of hair growth directly, we used the human keratin 14 promoter to target human vitamin D receptor expression to the … lameck ditto sukuma damu audioWebKeratin 14 is a keratin isoform strongly expressed by highly proliferative basal cells in chemically induced papilloma. The promoter of this keratin isoform was used to drive … lameck kamphindaWeb4 apr. 2024 · KRT14 keratin 14 [ (human)] Gene ID: 3861, updated on 5-Mar-2024. Summary. This gene encodes a member of the keratin family, the most diverse group of … jersey mike\u0027s carrboroWebThese transgenic mice have a tamoxifen inducible Cre-mediated recombination system driven by the human keratin 14 (KRT14) promoter, which is active in dividing cells of epidermis and some other stratified squamous epithelia.When crossed with a strain containing a loxP site flanked sequence of interest, the offspring can be used to generate … lameck ditto sukuma damu mp3Web14 feb. 1995 · The K14 keratin is an intermediate filament produced in squamous epithelia. This tissue-specific expression is directed by the promoter (pK14) of the K14 gene which has been used extensively to direct the expression of transgenes to the skin. Human K14 was cloned and the upstream sequence is presented. In transient transfections, pK14 … lameck humble lukanga